The Division of Breast Pathology consists of Dr. Stephen Moore (acting director), Dr. Saeed Bajestani and Dr. Debra Zynger. This has been an exciting year for the division for two major reasons: 1) The arrival of Dr. Bajestani in July 2010, from a breast pathology fellowship under the mentorship of Dr. Shahla Masood at the University of Florida, College Of Medicine in Jacksonville, and 2) The opening of the new JamesCare Comprehensive Breast Center in January 2011. With this opening came an ambitious undertaking of a daily multidisciplinary breast tumor conference to facilitate patient triage, with participation by surgical oncologists, medical oncologists, nurses, radiologists and pathologists (the latter via telepathology). The conference (commonly known as the “MMC”) is now held weekly on Fridays at 4:30 P.M. The Division also participates in a monthly breast-themed multidisciplinary tumor board held at the James Cancer Hospital, involving surgical and medical oncologists, radiologists, radiation therapists and others, during which recent cases and relevant medical information are discussed.
In the areas of service and quality assurance, this past year has seen the introduction of a new immunohistochemical stain, mammaglobin, which is one the few markers available that is highly specific for breast origin. To comply with CAP recommendations, we have implemented changes in reporting of estrogen and progesterone receptors, and also have implemented policies for cold ischemia time and duration of fixation of breast tissue.
In the area of teaching, we continue to provide one-on-one teaching to residents and medical students during case sign-out, as well as direct supervision of residents and pathology assistants in the gross room. The Division also provides a series of eight didactic lectures on breast pathology over the course of the 2-year resident lecture cycle.
In the research arena, in addition to several ongoing collaborative projects, Dr. Bajestani has been involved as a co-investigator in eight grant proposals including GRT00022635 “Targeting DNA repair pathways in breast cancer” (NIH), GRT00022638 “Stem cell and mesenchymal markers in breast circulating tumor cells” (NCI), GRT00023204 “Integration of transcription and translation in the breast tumor microenvironment” (NIH) and GRT00023408 “Distinct roles for stromal PTEN and p53 in suppressing mammary epithelial tumors” (NIH).